Most illustrious Lord, having sent to Your Lordship the eye unguent, which Messer Agnolo del Bufalo had requested on Your Excellency’s behalf, and having remembered that I did not send instructions for its use, here you will have them. First the sick person must wash their eyes with fresh water and dry them carefully, then he must place on the finger tip an amount of unguent about the size of a grain of wheat and open the eye, then spread the unguent on the eye-lids below and above rubbing the eye so that the unguent reaches all the corners. It must be used in this way until cured. I continually commend myself to your most illustrious [Excellency] this June 1521
Authorization to reproduce number 37-2011.
Federico Gonzaga (1500–1540)
became Marchese of Mantua after his father’s death in 1519, though his mother Isabella d’Este was regent for the first few years. Through skilled negotiations, in 1530 Federico was granted the title of duke of Mantua. Like Isabella, he fostered Antico’s career, rewarding him with grants of land and privileges.
Letter of Antico to Federico Gonzaga (salutation), June 1521, Archivio di Stato, Mantua