The image features an engraved portrait of a man named Thomas de Thomasi, shown from the chest up within an ornate oval frame. He is facing slightly to the right, with his head turned towards the viewer. The man has a full beard and curly hair, with a calm expression. He is wearing elaborate clothing with a ruffled collar, a draped robe or coat, and holds a medallion or pendant attached to a chain. Surrounding the portrait are intricate designs of scientific instruments like globes, books, and distillation apparatus, woven into the border with decorative scrolls and botanical elements. At the bottom, a plaque in Latin provides additional descriptors for Thomas de Thomasi. The image conveys a scholarly and scientific theme through its detailed engraving style.