Hugo Reisinger was born near Wiesbaden, Germany where he attended the Royal Gymnasium. He emigrated to the United States and was successfully engaged in the import business by 1890. He married Edmée Busch, daughter of Adolphus Busch (1842-1913), founder of the Anheuser-Busch Brewery. They had two sons, Walter Busch Reisinger and Curt Hugo Reisinger, a financier and philanthropist who endowed two chairs at Harvard. Reisinger, with his father-in-law, founded the institution which became the Busch-Reisinger Museum devoted to German art in Cambridge, Massachusetts. Upon his death, the bulk of Reisinger's estate was donated to charitable and educational institutions. A portrait of Hugo Reisinger by Anders Zorn is now in the NGA (1957.4.3).