Christ is shown here at the scene of his first miracle—the transformation of water into wine. He stands at the banquet table of a wedding, his right hand raised in a gesture of benediction, while a servant, pointing to the clay jars on the floor as if to explain what has just taken place, offers the bridal pair a goblet of the transformed liquid.
That the artist has absorbed the traditions of 15th–century Flemish painting is evident in his mastery of the oil technique and his meticulous rendering of texture and minute detail. Combined with these elements are purely Spanish ones, such as the solemn faces with downturned mouths and the recognizably Spanish costumes.
The unidentified artist's name is derived from his principal work, The Altarpiece of the Catholic Kings, of which this panel is a part. Visible among the heraldic devices are the insignia of provinces united by the marriage of Ferdinand and Isabella. The additional presence of the Holy Roman Emperor's coat–of–arms implies that The Marriage at Cana also alludes to two contemporary weddings significant in European history—those of Ferdinand and Isabella's daughter Juana in 1496 to, Philip the Fair, the son of the Holy Roman Emperor Maximilian I of Austria, and their son Juan in 1497 to the Holy Roman Emperor's daughter, Margaret of Austria.
More information on this painting can be found in the Gallery publication Spanish Paintings of the Fifteenth through Nineteenth Centuries, which is available as a free PDF https://www.nga.gov/content/dam/ngaweb/research/publications/pdfs/spanish-painting-15th-19th-centuries.pdf